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Zr-Catalyzed Synthesis of Tetrasubstituted 1,3-Diacylpyrroles from N-Acyl α-Aminoaldehydes and 1,3-Dicarbonyls

[Image: see text] A Zr-catalyzed synthesis of tetrasubstituted 1,3-diacylpyrroles is reported that employs the direct use of N-acyl α-aminoaldehydes with 1,3-dicarbonyl compounds. The products were formed in up to 88% yield and shown to be hydrolytically and configurationally stable under the reacti...

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Detalles Bibliográficos
Autores principales: Evans, Caria, Berkey, William J., Jones, Christopher W., France, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337043/
https://www.ncbi.nlm.nih.gov/pubmed/37294689
http://dx.doi.org/10.1021/acs.joc.3c00675