Hypothermic oxygenated perfusion attenuates DCD liver ischemia–reperfusion injury by activating the JAK2/STAT3/HAX1 pathway to regulate endoplasmic reticulum stress

BACKGROUND: Hepatic ischemia–reperfusion injury (IRI) in donation after cardiac death (DCD) donors is a major determinant of transplantation success. Endoplasmic reticulum (ER) stress plays a key role in hepatic IRI, with potential involvement of the Janus kinase 2/signal transducer and activator of...

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Detalles Bibliográficos
Autores principales: Yue, Pengpeng, Lv, Xiaoyan, You, Jian, Zou, Yongkang, luo, Jun, Lu, Zhongshan, Cao, Hankun, Liu, Zhongzhong, Fan, Xiaoli, Ye, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337067/
https://www.ncbi.nlm.nih.gov/pubmed/37438690
http://dx.doi.org/10.1186/s11658-023-00466-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337067/
https://www.ncbi.nlm.nih.gov/pubmed/37438690
http://dx.doi.org/10.1186/s11658-023-00466-5

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