DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironment

Chordomas are rare tumors of notochord remnants, occurring mainly in the sacrum and skull base. Despite of their unusually slow growth, chordomas are highly invasive and the involvement of adjacent critical structures causes treatment challenges. Due to the low incidence, the molecular pathogenesis...

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Detalles Bibliográficos
Autores principales: Baluszek, Szymon, Kober, Paulina, Rusetska, Natalia, Wągrodzki, Michał, Mandat, Tomasz, Kunicki, Jacek, Bujko, Mateusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337070/
https://www.ncbi.nlm.nih.gov/pubmed/37434245
http://dx.doi.org/10.1186/s40478-023-01610-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337070/
https://www.ncbi.nlm.nih.gov/pubmed/37434245
http://dx.doi.org/10.1186/s40478-023-01610-0

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