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AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells

BACKGROUND: Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulum (ER) stress is a hallmark of sepsis-related alveolar epi...

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Detalles Bibliográficos
Autores principales: Becker, Eugene, Husain, Maroof, Bone, Nathaniel, Smith, Samuel, Morris, Peter, Zmijewski, Jaroslaw W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337128/
https://www.ncbi.nlm.nih.gov/pubmed/37438806
http://dx.doi.org/10.1186/s12931-023-02483-6