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Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes

BACKGROUND: As a result of aging, skeletal muscle undergoes atrophy and a decrease in function. This age-related skeletal muscle weakness is known as “sarcopenia”. Sarcopenia is part of the frailty observed in humans. In order to discover treatments for sarcopenia, it is necessary to determine appro...

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Detalles Bibliográficos
Autores principales: Shavlakadze, Tea, Xiong, Kun, Mishra, Shawn, McEwen, Corissa, Gadi, Abhilash, Wakai, Matthew, Salmon, Hunter, Stec, Michael J., Negron, Nicole, Ni, Min, Wei, Yi, Atwal, Gurinder S., Bai, Yu, Glass, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337157/
https://www.ncbi.nlm.nih.gov/pubmed/37438807
http://dx.doi.org/10.1186/s13395-023-00321-3