NLRP3–GABA signaling pathway contributes to the pathogenesis of impulsive-like behaviors and cognitive deficits in aged mice

BACKGROUND: Perioperative neurocognitive disorders (PND), such as delirium and cognitive impairment, are commonly encountered complications in aged patients. The inhibitory neurotransmitter γ-aminobutyric acid (GABA) is aberrantly synthesized from reactive astrocytes following inflammatory stimulati...

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Detalles Bibliográficos
Autores principales: Wang, Lu-Ying, Wang, Xu-Peng, Lv, Jin-Meng, Shan, Yu-Dong, Jia, Shi-Yan, Yu, Zhi-Fang, Miao, Hui-Tao, Xin, Yue, Zhang, Dong-Xue, Zhang, Li-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337164/
https://www.ncbi.nlm.nih.gov/pubmed/37434240
http://dx.doi.org/10.1186/s12974-023-02845-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337164/
https://www.ncbi.nlm.nih.gov/pubmed/37434240
http://dx.doi.org/10.1186/s12974-023-02845-3

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