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RUNX3 regulates the susceptibility against EGFR-targeted non-small cell lung cancer therapy using (47)Sc-conjugated cetuximab

BACKGROUND: Radioimmunotherapy with cetuximab and conjugates with various radioisotopes is a feasible treatment option for different tumor models. Scandium-47 ((47)Sc), one of several β(−)-particle-emitting radioisotopes, displays favorable physical and chemical properties for conjugation to monoclo...

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Detalles Bibliográficos
Autores principales: Kim, Da-Mi, Lee, So-Young, Lim, Jae-Cheong, Cho, Eun-Ha, Park, Ul-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337176/
https://www.ncbi.nlm.nih.gov/pubmed/37438719
http://dx.doi.org/10.1186/s12885-023-11161-1