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Mapping genetic variants for nonsense-mediated mRNA decay regulation across human tissues
BACKGROUND: Nonsense-mediated mRNA decay (NMD) was originally conceived as an mRNA surveillance mechanism to prevent the production of potentially deleterious truncated proteins. Research also shows NMD is an important post-transcriptional gene regulation mechanism selectively targeting many non-abe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337212/ https://www.ncbi.nlm.nih.gov/pubmed/37434206 http://dx.doi.org/10.1186/s13059-023-03004-w |