Mapping genetic variants for nonsense-mediated mRNA decay regulation across human tissues

BACKGROUND: Nonsense-mediated mRNA decay (NMD) was originally conceived as an mRNA surveillance mechanism to prevent the production of potentially deleterious truncated proteins. Research also shows NMD is an important post-transcriptional gene regulation mechanism selectively targeting many non-abe...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337212/
https://www.ncbi.nlm.nih.gov/pubmed/37434206
http://dx.doi.org/10.1186/s13059-023-03004-w

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