AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues

[Image: see text] Recent advances in targeted covalent inhibitors have aroused significant interest for their potential in drug development for difficult therapeutic targets. Proteome-wide profiling of functional residues is an integral step of covalent drug discovery aimed at defining actionable si...

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Detalles Bibliográficos
Autores principales: Ma, Taylur P., Izrael-Tomasevic, Anita, Mroue, Rana, Budayeva, Hanna, Malhotra, Sushant, Raisner, Ryan, Evangelista, Marie, Rose, Christopher M., Kirkpatrick, Donald S., Yu, Kebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337260/
https://www.ncbi.nlm.nih.gov/pubmed/37285454
http://dx.doi.org/10.1021/acs.jproteome.2c00703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337260/
https://www.ncbi.nlm.nih.gov/pubmed/37285454
http://dx.doi.org/10.1021/acs.jproteome.2c00703

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