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AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues
[Image: see text] Recent advances in targeted covalent inhibitors have aroused significant interest for their potential in drug development for difficult therapeutic targets. Proteome-wide profiling of functional residues is an integral step of covalent drug discovery aimed at defining actionable si...
Autores principales: | Ma, Taylur P., Izrael-Tomasevic, Anita, Mroue, Rana, Budayeva, Hanna, Malhotra, Sushant, Raisner, Ryan, Evangelista, Marie, Rose, Christopher M., Kirkpatrick, Donald S., Yu, Kebing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337260/ https://www.ncbi.nlm.nih.gov/pubmed/37285454 http://dx.doi.org/10.1021/acs.jproteome.2c00703 |
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