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KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer
BACKGROUND: Accumulating studies demonstrated that resistance of colon cancer (CC) to 5-fluorouracil (5-FU) contributes to adverse prognosis. We investigated how Kruppel-like factor 4 (KLF4) affected 5-FU resistance and autophagy in CC cells. METHODS: KLF4 expression and its downstream target gene R...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337498/ https://www.ncbi.nlm.nih.gov/pubmed/37431852 http://dx.doi.org/10.1080/15384047.2023.2226353 |