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KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer

BACKGROUND: Accumulating studies demonstrated that resistance of colon cancer (CC) to 5-fluorouracil (5-FU) contributes to adverse prognosis. We investigated how Kruppel-like factor 4 (KLF4) affected 5-FU resistance and autophagy in CC cells. METHODS: KLF4 expression and its downstream target gene R...

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Detalles Bibliográficos
Autores principales:	Zheng, Yu, Wu, Jiansheng, Chen, Hong, Lin, Dajia, Chen, Hongyuan, Zheng, Junyin, Xia, Haoyun, Huang, Liangxiang, Zeng, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337498/ https://www.ncbi.nlm.nih.gov/pubmed/37431852 http://dx.doi.org/10.1080/15384047.2023.2226353

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