Phenylpropionic acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity

The gut microbiota affects hepatic drug metabolism. However, gut microbial factors modulating hepatic drug metabolism are largely unknown. In this study, using a mouse model of acetaminophen (APAP)-induced hepatotoxicity, we identified a gut bacterial metabolite that controls the hepatic expression...

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Detalles Bibliográficos
Autores principales: Cho, Sungjoon, Yang, Xiaotong, Won, Kyoung-Jae, Leone, Vanessa A., Chang, Eugene B., Guzman, Grace, Ko, Yeonju, Bae, Ok-Nam, Lee, Hyunwoo, Jeong, Hyunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337503/
https://www.ncbi.nlm.nih.gov/pubmed/37431867
http://dx.doi.org/10.1080/19490976.2023.2231590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337503/
https://www.ncbi.nlm.nih.gov/pubmed/37431867
http://dx.doi.org/10.1080/19490976.2023.2231590

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