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Gut microbiota-related bile acid metabolism-FXR/TGR5 axis impacts the response to anti-α4β7-integrin therapy in humanized mice with colitis

The gut microbiota and bile acid metabolism are key determinants of the response of inflammatory bowel disease to biologic therapy. However, the molecular mechanisms underlying the interactions between the response to anti-α4β7-integrin therapy and the gut microbiota and bile acid metabolism remain...

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Detalles Bibliográficos
Autores principales: Han, Bing, Lv, Xiaodan, Liu, Gengfeng, Li, Shiquan, Fan, Junhua, Chen, Lan, Huang, Zhixi, Lin, Guangfu, Xu, Xiaofang, Huang, Ziqian, Zhan, Lingling, Lv, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337508/
https://www.ncbi.nlm.nih.gov/pubmed/37431863
http://dx.doi.org/10.1080/19490976.2023.2232143