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METABOLOGENOMIC CHARACTERIZATION UNCOVERS HETEROGENEITY AMONG IDH MUTANT GLIOMAS

Mutations in isocitrate dehydrogenase (IDH) enzymes are recognised to drive the molecular footprint of diffuse gliomas, and patients with IDH-mutant gliomas have overall favorable outcomes compared to patients with IDH wildtype tumors. Nonetheless, survival can vary widely even amongst patients with...

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Detalles Bibliográficos
Autores principales: Ajisebutu, Andrew, Nassiri, Farshad, Wang, Justin Z, Mamatjan, Yasin, Nejad, Romina, Patil, Vikas, Liu, Jeff, Voisin, Mathew R, Mansouri, Sheila, Karimi, Shirin, Chakravarthy, Ankur, Chen, Eric, De Carvalho, Daniel D, Aldape, Kenneth, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337532/
http://dx.doi.org/10.1093/noajnl/vdad071.001