OSMR INTERACTOME MAPPING REVEALS THE SIGNIFICANCE OF A CHLORIDE CHANNEL IN CYTOKINE REGULATION AND BRAIN TUMOUR STEM CELL SELF-RENEWAL

Oncostatin M Receptor (OSMR) is a key regulator of brain tumour stem cell (BTSC) self-renewal and glioblastoma (GB) tumourigenesis. This receptor is found in a complex with Epidermal Growth Factor Receptor variant III (EGFRvIII) and orchestrates a positive feedback loop with STAT3. OSMR also regulat...

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Detalles Bibliográficos
Autores principales: Randhawa, Kamaldeep, Snider, Jamie, Raco, Laura, Stagljar, Igor, Jahani-Asl, Arezu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Posters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337544/
http://dx.doi.org/10.1093/noajnl/vdad071.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337544/
http://dx.doi.org/10.1093/noajnl/vdad071.045

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