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SONIC HEDGEHOG (SHH) PROMOTES BLOOD-BRAIN BARRIER (BBB) INTEGRITY IN DIFFUSE MIDLINE GLIOMA OF THE PONS

Diffuse Midline Glioma of the Pons (DMG-P) is the most common brainstem tumor in children and is universally lethal in this age group. The intact Blood-Brain Barrier (BBB) in these tumors are believed to play a major role in preventing systemically administered therapeutic agents from reaching thera...

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Detalles Bibliográficos
Autores principales: Line, Stacey, Sajesh, Babu V, Yathindranath, Vinith, On, Nog H, Miller, Donald W, Vanan, Magimairajan Issai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337551/
http://dx.doi.org/10.1093/noajnl/vdad071.010