Cargando…

SONIC HEDGEHOG (SHH) PROMOTES BLOOD-BRAIN BARRIER (BBB) INTEGRITY IN DIFFUSE MIDLINE GLIOMA OF THE PONS

Diffuse Midline Glioma of the Pons (DMG-P) is the most common brainstem tumor in children and is universally lethal in this age group. The intact Blood-Brain Barrier (BBB) in these tumors are believed to play a major role in preventing systemically administered therapeutic agents from reaching thera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Line, Stacey, Sajesh, Babu V, Yathindranath, Vinith, On, Nog H, Miller, Donald W, Vanan, Magimairajan Issai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Pediatric Oral Presentations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337551/ http://dx.doi.org/10.1093/noajnl/vdad071.010

Ejemplares similares

Spermidine/Spermine N1-Acetyltransferase 1 (SAT1)—A Potential Gene Target for Selective Sensitization of Glioblastoma Cells Using an Ionizable Lipid Nanoparticle to Deliver siRNA
por: Yathindranath, Vinith, et al.
Publicado: (2022)

DIPG in Children – What Can We Learn from the Past?
por: Vanan, Magimairajan Issai, et al.
Publicado: (2015)

Regulation of Cholesterol Binding to the Receptor Patched1 by its interactions With the Ligand Sonic Hedgehog (Shh)
por: Zhong, Changqing, et al.
Publicado: (2022)

Management of Inoperable Supra-Sellar Low-Grade Glioma With BRAF Mutation in Young Children
por: Howden, Kaitlyn, et al.
Publicado: (2021)

Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source
por: Martínez, Constanza, et al.
Publicado: (2013)

Is Sonic Hedgehog Involved in Human Fracture Healing? - A Prospective Study on Local and Systemic Concentrations of SHH
por: Eipeldauer, Stefan, et al.
Publicado: (2014)

Upfront BRAF/MEK inhibitors for treatment of high-grade glioma: A case report and review of the literature
por: Arbour, Gabrielle, et al.
Publicado: (2022)

Sonic hedgehog (Shh)/Gli modulates the spatial organization of neuroepithelial cell proliferation in the developing chick optic tectum
por: Rapacioli, Melina, et al.
Publicado: (2012)

Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer
por: Noman, A. S., et al.
Publicado: (2017)

Correction: Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source
por: Martínez, Constanza, et al.
Publicado: (2020)

LGG-23. EXCELLENT CLINICAL / RADIOLOGICAL RESPONSE TO BRAF INHIBITION IN A YOUNG CHILD WITH IN-OPERABLE SUPRA-SELLAR PILOCYTIC ASTROCYTOMA
por: Chapman, Stacy, et al.
Publicado: (2020)

Sonic hedgehog (SHH) signaling improves the angiogenic potential of Wharton’s jelly-derived mesenchymal stem cells (WJ-MSC)
por: Zavala, Gabriela, et al.
Publicado: (2017)

ALKAL1 gene silencing prevents colorectal cancer progression via suppressing Sonic Hedgehog (SHH) signaling pathway
por: Chen, Shasha, et al.
Publicado: (2021)

Sonic Hedgehog in SCLC
por: Laukkanen, Mikko O., et al.
Publicado: (2015)

Lentiviral-mediated Shh reverses the adverse effects of high glucose on osteoblast function and promotes bone formation via Sonic hedgehog signaling
por: Jiang, Zhu-Ling, et al.
Publicado: (2019)

Sonic hedgehog signaling in astrocytes
por: Hill, Steven A., et al.
Publicado: (2020)

Sustained and durable response with Alisertib monotherapy in the treatment of relapsed Atypical Teratoid Rhabdoid Tumor (ATRT)
por: Howden, Kaitlyn, et al.
Publicado: (2022)

Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling
por: Petrova, Elissaveta, et al.
Publicado: (2013)

Cleavage activates Dispatched for Sonic Hedgehog ligand release
por: Stewart, Daniel P, et al.
Publicado: (2018)

Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors
por: Sajesh, Babu V., et al.
Publicado: (2019)

DDEL-06. Drug Delivery to the Pons Using Short-Pulse Focused Ultrasound and Microbubble Exposure for the Treatment of Diffuse Midline Glioma
por: Chattenton, Dani, et al.
Publicado: (2022)

Evaluating drug distribution in children and young adults with diffuse midline glioma of the pons (DIPG) treated with convection-enhanced drug delivery
por: Szychot, Elwira, et al.
Publicado: (2023)

Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain Tumorigenesis
por: Ward, Stacey A., et al.
Publicado: (2015)

Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma
por: Caimano, Miriam, et al.
Publicado: (2021)

Regulation of Thalamic Development by Sonic Hedgehog
por: Epstein, Douglas J.
Publicado: (2012)

Probing extracellular Sonic hedgehog in neurons
por: Eitan, Erez, et al.
Publicado: (2016)

Sonic Hedgehog Signaling in Thyroid Cancer
por: Xu, Xiulong, et al.
Publicado: (2017)

A highlight on Sonic hedgehog pathway
por: Carballo, Gabriela Basile, et al.
Publicado: (2018)

Sonic Hedgehog Signaling and Development of the Dentition
por: Seppala, Maisa, et al.
Publicado: (2017)

Sonic Hedgehog Signaling in Limb Development
por: Tickle, Cheryll, et al.
Publicado: (2017)

Sonic hedgehog expression in the postnatal brain
por: Rivell, Aileen, et al.
Publicado: (2019)

Sonic Hedgehog Signaling and Tooth Development
por: Hosoya, Akihiro, et al.
Publicado: (2020)

Sonic hedgehog is a potent chemoattractant for human monocytes: diabetes mellitus inhibits Sonic hedgehog-induced monocyte chemotaxis
por: Dunaeva, Marina, et al.
Publicado: (2009)

Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties
por: Irimia, Manuel, et al.
Publicado: (2012)

Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures
por: Himmelstein, Diana S, et al.
Publicado: (2010)

Developmental pathways: Sonic hedgehog-Patched-GLI.
por: Walterhouse, D O, et al.
Publicado: (1999)

Ontogenetic Expression of Sonic Hedgehog in the Chicken Subpallium
por: Bardet, Sylvia M., et al.
Publicado: (2010)

Sonic hedgehog promotes autophagy in hippocampal neurons
por: Petralia, Ronald S., et al.
Publicado: (2013)

Sonic hedgehog signaling in the development of the mouse hypothalamus
por: Blaess, Sandra, et al.
Publicado: (2015)

Sonic Hedgehog: a lipid speciated hormone?
por: Long, Jun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vblgoobu6d3b2lhqfugn8t7bfv