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TARGETING CANCER STEM CELLS WITH A CDK2 INHIBITOR IN GLIOBLASTOMA

Glioblastoma (GB) is the most common and aggressive adult brain tumor with no cure. Brain tumor stem cells (BTSCs) are a rare population of self-renewing multipotent stem cells in GB that contribute to tumorigenesis, therapeutic resistance, and tumour recurrence. Here, we report a CDK2 inhibitor tha...

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Detalles Bibliográficos
Autores principales: Mahmnoudian, Elham, Qu, Dianbo, Lotfipour, Farzaneh, Jahani-Asl, Arezu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337562/
http://dx.doi.org/10.1093/noajnl/vdad071.049