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Case report: Use of therapeutic drug monitoring and pharmacogenetic testing as opportunities to individualize care in a case of flecainide toxicity after fetal supraventricular tachycardia

Flecainide is a class IC antiarrhythmic utilized in prophylaxis of refractory paroxysmal supraventricular tachycardias in pediatric populations. Despite being a highly effective agent, its narrow therapeutic index increases the risk of toxicity and proarrhythmic events, including wide-complex tachyc...

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Detalles Bibliográficos
Autores principales: Palmen, Ronald, Sandritter, Tracy, Malloy-Walton, Lindsey, Follansbee, Christopher, Wagner, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337585/
https://www.ncbi.nlm.nih.gov/pubmed/37449265
http://dx.doi.org/10.3389/fped.2023.1168619