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Magnetic resonance imaging and ultrasound elastography in the context of preclinical pharmacological research: significance for the 3R principles

The 3Rs principles—reduction, refinement, replacement—are at the core of preclinical research within drug discovery, which still relies to a great extent on the availability of models of disease in animals. Minimizing their distress, reducing their number as well as searching for means to replace th...

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Detalles Bibliográficos
Autores principales: Obrecht, Michael, Zurbruegg, Stefan, Accart, Nathalie, Lambert, Christian, Doelemeyer, Arno, Ledermann, Birgit, Beckmann, Nicolau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337591/
https://www.ncbi.nlm.nih.gov/pubmed/37448960
http://dx.doi.org/10.3389/fphar.2023.1177421