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Magnetic resonance imaging and ultrasound elastography in the context of preclinical pharmacological research: significance for the 3R principles
The 3Rs principles—reduction, refinement, replacement—are at the core of preclinical research within drug discovery, which still relies to a great extent on the availability of models of disease in animals. Minimizing their distress, reducing their number as well as searching for means to replace th...
Autores principales: | Obrecht, Michael, Zurbruegg, Stefan, Accart, Nathalie, Lambert, Christian, Doelemeyer, Arno, Ledermann, Birgit, Beckmann, Nicolau |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337591/ https://www.ncbi.nlm.nih.gov/pubmed/37448960 http://dx.doi.org/10.3389/fphar.2023.1177421 |
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