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Enantioselective isothiourea-catalysed reversible Michael addition of aryl esters to 2-benzylidene malononitriles

Catalytic enantioselective transformations usually rely upon optimal enantioselectivity being observed in kinetically controlled reaction processes, with energy differences between diastereoisomeric transition state energies translating to stereoisomeric product ratios. Herein, stereoselectivity res...

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Detalles Bibliográficos
Autores principales: Nimmo, Alastair J., Bitai, Jacqueline, Young, Claire M., McLaughlin, Calum, Slawin, Alexandra M. Z., Cordes, David B., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337745/
https://www.ncbi.nlm.nih.gov/pubmed/37449062
http://dx.doi.org/10.1039/d3sc02101g