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Palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes: synthesis of cyclopropane-fused γ-lactams

A palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes via C(sp(3))–H activation has been developed for the synthesis of cyclopropane-fused γ-lactams. The presented strategy proceeds in a selective and 100% atom-economical manner. A range of cyclopropane-fused γ-lactams w...

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Detalles Bibliográficos
Autores principales: Lin, Han-Ze, Qi, Zhuang, Wu, Qi-Min, Jiang, Yong-Yu, Peng, Jin-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337766/
https://www.ncbi.nlm.nih.gov/pubmed/37449077
http://dx.doi.org/10.1039/d3sc02168h