GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression

T-bet-expressing Th17 (T-bet(+)RORγt(+)) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. However, the upstream regulatory mechanisms that c...

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Detalles Bibliográficos
Autores principales: Butcher, Matthew J., Gurram, Rama Krishna, Zhu, Xiaoliang, Chen, Xi, Hu, Gangqing, Lazarevic, Vanja, Zhao, Keji, Zhu, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337884/
https://www.ncbi.nlm.nih.gov/pubmed/37449212
http://dx.doi.org/10.3389/fimmu.2023.1186580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337884/
https://www.ncbi.nlm.nih.gov/pubmed/37449212
http://dx.doi.org/10.3389/fimmu.2023.1186580

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