Cargando…
GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression
T-bet-expressing Th17 (T-bet(+)RORγt(+)) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. However, the upstream regulatory mechanisms that c...
Autores principales: | Butcher, Matthew J., Gurram, Rama Krishna, Zhu, Xiaoliang, Chen, Xi, Hu, Gangqing, Lazarevic, Vanja, Zhao, Keji, Zhu, Jinfang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337884/ https://www.ncbi.nlm.nih.gov/pubmed/37449212 http://dx.doi.org/10.3389/fimmu.2023.1186580 |
Ejemplares similares
-
Gata3
(ZsG) and Gata3
(ZsG-fl): Novel murine Gata3 reporter alleles for identifying and studying Th2 cells and ILC2s in vivo
por: Gurram, Rama K., et al.
Publicado: (2022) -
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation
por: Fang, Difeng, et al.
Publicado: (2018) -
Crosstalk between ILC2s and Th2 cells varies among mouse models
por: Gurram, Rama K., et al.
Publicado: (2023) -
The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination
por: Yu, Fang, et al.
Publicado: (2018) -
Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
por: Lazarus, Hillard M., et al.
Publicado: (2023)