Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

During intestinal organogenesis, equipotent epithelial progenitors mature into phenotypically distinct stem cells that are responsible for lifelong maintenance of the tissue. While the morphological changes associated with the transition are well characterized, the molecular mechanisms underpinning...

Descripción completa

Detalles Bibliográficos
Autores principales: Pikkupeura, Laura M., Bressan, Raul B., Guiu, Jordi, Chen, Yun, Maimets, Martti, Mayer, Daniela, Schweiger, Pawel J., Hansen, Stine L., Maciag, Grzegorz J., Larsen, Hjalte L., Lõhmussaar, Kadi, Pedersen, Marianne Terndrup, Teves, Joji M. Yap, Bornholdt, Jette, Benes, Vladimir, Sandelin, Albin, Jensen, Kim B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337905/
https://www.ncbi.nlm.nih.gov/pubmed/37436997
http://dx.doi.org/10.1126/sciadv.adf9460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337905/
https://www.ncbi.nlm.nih.gov/pubmed/37436997
http://dx.doi.org/10.1126/sciadv.adf9460

Ejemplares similares