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Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation
During intestinal organogenesis, equipotent epithelial progenitors mature into phenotypically distinct stem cells that are responsible for lifelong maintenance of the tissue. While the morphological changes associated with the transition are well characterized, the molecular mechanisms underpinning...
Autores principales: | Pikkupeura, Laura M., Bressan, Raul B., Guiu, Jordi, Chen, Yun, Maimets, Martti, Mayer, Daniela, Schweiger, Pawel J., Hansen, Stine L., Maciag, Grzegorz J., Larsen, Hjalte L., Lõhmussaar, Kadi, Pedersen, Marianne Terndrup, Teves, Joji M. Yap, Bornholdt, Jette, Benes, Vladimir, Sandelin, Albin, Jensen, Kim B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337905/ https://www.ncbi.nlm.nih.gov/pubmed/37436997 http://dx.doi.org/10.1126/sciadv.adf9460 |
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