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A cooperative network at the nuclear envelope counteracts LINC-mediated forces during oogenesis in C. elegans

Oogenesis involves transduction of mechanical forces from the cytoskeleton to the nuclear envelope (NE). In Caenorhabditis elegans, oocyte nuclei lacking the single lamin protein LMN-1 are vulnerable to collapse under forces mediated through LINC (linker of nucleoskeleton and cytoskeleton) complexes...

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Detalles Bibliográficos
Autores principales: Liu, Chenshu, Rex, Rachel, Lung, Zoe, Wang, John S., Wu, Fan, Kim, Hyung Jun, Zhang, Liangyu, Sohn, Lydia L., Dernburg, Abby F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337908/
https://www.ncbi.nlm.nih.gov/pubmed/37436986
http://dx.doi.org/10.1126/sciadv.abn5709