The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammals

Species differences in the host factor ANP32A/B result in the restriction of avian influenza virus polymerase (vPol) in mammalian cells. Efficient replication of avian influenza viruses in mammalian cells often requires adaptive mutations, such as PB2-E627K, to enable the virus to use mammalian ANP3...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Liuke, Kong, Huihui, Yu, Mengmeng, Zhang, Zhenyu, Zhang, Haili, Na, Lei, Qu, Yuxing, Zhang, Yuan, Chen, Hualan, Wang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337910/
https://www.ncbi.nlm.nih.gov/pubmed/37436988
http://dx.doi.org/10.1126/sciadv.adg5175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337910/
https://www.ncbi.nlm.nih.gov/pubmed/37436988
http://dx.doi.org/10.1126/sciadv.adg5175

Ejemplares similares