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IGFBP2 secretion by mammary adipocytes limits breast cancer invasion

The progression of noninvasive ductal carcinoma in situ to invasive ductal carcinoma for patients with breast cancer results in a significantly poorer prognosis and is the precursor to metastatic disease. In this work, we have identified insulin-like growth factor–binding protein 2 (IGFBP2) as a pot...

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Detalles Bibliográficos
Autores principales: Conway, James R. W., Dinç, Defne D., Follain, Gautier, Paavolainen, Oona, Kaivola, Jasmin, Boström, Pia, Hartiala, Pauliina, Peuhu, Emilia, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337915/
https://www.ncbi.nlm.nih.gov/pubmed/37436978
http://dx.doi.org/10.1126/sciadv.adg1840