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PINK1: From Parkinson’s disease to mitophagy and back again

The genetics of Parkinson’s disease has been key to unravelling the PINK1-dependent mitophagy process. Here, we discuss the implications of a 2010 PLOS Biology paper that shed light on the functional importance of PINK1 in the mitophagy cascade.

Detalles Bibliográficos
Autores principales: O’Callaghan, Benjamin, Hardy, John, Plun-Favreau, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337960/
https://www.ncbi.nlm.nih.gov/pubmed/37384773
http://dx.doi.org/10.1371/journal.pbio.3002196