Targeting the MR1-MAIT cell axis improves vaccine efficacy and affords protection against viral pathogens

Mucosa-associated invariant T (MAIT) cells are MR1-restricted, innate-like T lymphocytes with tremendous antibacterial and immunomodulatory functions. Additionally, MAIT cells sense and respond to viral infections in an MR1-independent fashion. However, whether they can be directly targeted in immun...

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Detalles Bibliográficos
Autores principales: Rashu, Rasheduzzaman, Ninkov, Marina, Wardell, Christine M., Benoit, Jenna M., Wang, Nicole I., Meilleur, Courtney E., D’Agostino, Michael R., Zhang, Ali, Feng, Emily, Saeedian, Nasrin, Bell, Gillian I., Vahedi, Fatemeh, Hess, David A., Barr, Stephen D., Troyer, Ryan M., Kang, Chil-Yong, Ashkar, Ali A., Miller, Matthew S., Haeryfar, S. M. Mansour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337970/
https://www.ncbi.nlm.nih.gov/pubmed/37384813
http://dx.doi.org/10.1371/journal.ppat.1011485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337970/
https://www.ncbi.nlm.nih.gov/pubmed/37384813
http://dx.doi.org/10.1371/journal.ppat.1011485

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