Regulation of chromatin microphase separation by binding of protein complexes

We show evidence of the association of RNA polymerase II (RNAP) with chromatin in a core-shell organization, reminiscent of microphase separation where the cores comprise dense chromatin and the shell, RNAP and chromatin with low density. These observations motivate our physical model for the regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Adame-Arana, Omar, Bajpai, Gaurav, Lorber, Dana, Volk, Talila, Safran, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338032/
https://www.ncbi.nlm.nih.gov/pubmed/37436818
http://dx.doi.org/10.7554/eLife.82983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338032/
https://www.ncbi.nlm.nih.gov/pubmed/37436818
http://dx.doi.org/10.7554/eLife.82983

Ejemplares similares