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Optogenetic modulation of hippocampal oscillations ameliorates spatial cognition and hippocampal dysrhythmia following early-life seizures

There is increasing human and animal evidence that brain oscillations play a critical role in the development of spatial cognition. In rat pups, disruption of hippocampal rhythms via optogenetic stimulation during the critical period for memory development impairs spatial cognition. Early-life seizu...

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Detalles Bibliográficos
Autores principales: Velasquez, Francisco, Dickson, Conor, Kloc, Michelle L., Schneur, Carmel A., Barry, Jeremy M., Holmes, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338061/
https://www.ncbi.nlm.nih.gov/pubmed/36720444
http://dx.doi.org/10.1016/j.nbd.2023.106021