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Synergism between x-ray crystallography and NMR residual dipolar couplings in characterizing protein dynamics

The important role of structural dynamics in protein function is widely recognized. Thermal or B-factors and their anisotropy, seen in x-ray analysis of protein structures, report on the presence of atomic coordinate heterogeneity that can be attributed to motion. However, their quantitative evaluat...

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Detalles Bibliográficos
Autores principales: Shen, Yang, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Crystallographic Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338066/
https://www.ncbi.nlm.nih.gov/pubmed/37448874
http://dx.doi.org/10.1063/4.0000192