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Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway

BACKGROUND: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. METHODS: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant restoration. Osteogenic and adipogenic experim...

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Detalles Bibliográficos
Autores principales: Zhang, Zeliang, Shang, Wei, Zhao, Xicong, Lin, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338146/
https://www.ncbi.nlm.nih.gov/pubmed/37448850
http://dx.doi.org/10.1016/j.reth.2023.06.015