Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors

Karyopherins mediate the movement between the nucleus and cytoplasm of specific proteins in diverse cellular processes. Through a loss-of-function approach, we here examine the role of Karyopherin Subunit Alpha 2 (Kpna2) in spermatogenesis. Knockout male mice exhibited reduced body size and sperm mo...

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Detalles Bibliográficos
Autores principales: Navarrete-López, Paula, Maroto, María, Pericuesta, Eva, Fernández-González, Raúl, Lombó, Marta, Ramos-Ibeas, Priscila, Gutiérrez-Adán, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338237/
https://www.ncbi.nlm.nih.gov/pubmed/37456838
http://dx.doi.org/10.1016/j.isci.2023.107134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338237/
https://www.ncbi.nlm.nih.gov/pubmed/37456838
http://dx.doi.org/10.1016/j.isci.2023.107134

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