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Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors
Karyopherins mediate the movement between the nucleus and cytoplasm of specific proteins in diverse cellular processes. Through a loss-of-function approach, we here examine the role of Karyopherin Subunit Alpha 2 (Kpna2) in spermatogenesis. Knockout male mice exhibited reduced body size and sperm mo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338237/ https://www.ncbi.nlm.nih.gov/pubmed/37456838 http://dx.doi.org/10.1016/j.isci.2023.107134 |