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Peripheral blood mononuclear cell hyperresponsiveness in patients with premature myocardial infarction without traditional risk factors

An increasing number of patients develop an atherothrombotic myocardial infarction (MI) in the absence of standard modifiable risk factors (SMuRFs). Monocytes and macrophages regulate the development of atherosclerosis, and monocytes can adopt a long-term hyperinflammatory phenotype by epigenetic re...

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Detalles Bibliográficos
Autores principales: Mol, Jan-Quinten, van Tuijl, Julia, Bekkering, Siroon, van der Heijden, Charlotte D.C.C., Damen, Sander A.J., Cossins, Benjamin C., van Emst, Liesbeth, Nielen, Tim M., Rodwell, Laura, Li, Yang, Pop, Gheorghe A.M., Netea, Mihai G., van Royen, Niels, Riksen, Niels P., El Messaoudi, Saloua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338301/
https://www.ncbi.nlm.nih.gov/pubmed/37456854
http://dx.doi.org/10.1016/j.isci.2023.107183