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Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells

Tet2 is a member of the Ten-eleven translocation (Tet1/2/3) family of enzymes and is expressed in embryonic stem cells (ESCs). It demethylates DNA (catalytic functions) and partners with chromatin modifiers (noncatalytic functions) to regulate genes. However, the significance of these functions in E...

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Detalles Bibliográficos
Autores principales: Flores, Julio C., Sidoli, Simone, Dawlaty, Meelad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338317/
https://www.ncbi.nlm.nih.gov/pubmed/37456851
http://dx.doi.org/10.1016/j.isci.2023.107170