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Histone modifications regulate pioneer transcription factor cooperativity

Pioneer transcription factors have the ability to access DNA in compacted chromatin(1). Multiple transcription factors can bind together to a regulatory element in a cooperative way, and cooperation between the pioneer transcription factors OCT4 (also known as POU5F1) and SOX2 is important for pluri...

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Detalles Bibliográficos
Autores principales: Sinha, Kalyan K., Bilokapic, Silvija, Du, Yongming, Malik, Deepshikha, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338341/
https://www.ncbi.nlm.nih.gov/pubmed/37225990
http://dx.doi.org/10.1038/s41586-023-06112-6