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Cooperation between bHLH transcription factors and histones for DNA access

The basic helix–loop–helix (bHLH) family of transcription factors recognizes DNA motifs known as E-boxes (CANNTG) and includes 108 members(1). Here we investigate how chromatinized E-boxes are engaged by two structurally diverse bHLH proteins: the proto-oncogene MYC-MAX and the circadian transcripti...

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Detalles Bibliográficos
Autores principales: Michael, Alicia K., Stoos, Lisa, Crosby, Priya, Eggers, Nikolas, Nie, Xinyu Y., Makasheva, Kristina, Minnich, Martina, Healy, Kelly L., Weiss, Joscha, Kempf, Georg, Cavadini, Simone, Kater, Lukas, Seebacher, Jan, Vecchia, Luca, Chakraborty, Deyasini, Isbel, Luke, Grand, Ralph S., Andersch, Florian, Fribourgh, Jennifer L., Schübeler, Dirk, Zuber, Johannes, Liu, Andrew C., Becker, Peter B., Fierz, Beat, Partch, Carrie L., Menet, Jerome S., Thomä, Nicolas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338342/
https://www.ncbi.nlm.nih.gov/pubmed/37407816
http://dx.doi.org/10.1038/s41586-023-06282-3