Relaxed targeting rules help PIWI proteins silence transposons

In eukaryotes, small RNA guides, such as small interfering RNAs and microRNAs, direct AGO-clade Argonaute proteins to regulate gene expression and defend the genome against external threats. Only animals make a second clade of Argonaute proteins: PIWI proteins. PIWI proteins use PIWI-interacting RNA...

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Detalles Bibliográficos
Autores principales: Gainetdinov, Ildar, Vega-Badillo, Joel, Cecchini, Katharine, Bagci, Ayca, Colpan, Cansu, De, Dipayan, Bailey, Shannon, Arif, Amena, Wu, Pei-Hsuan, MacRae, Ian J., Zamore, Phillip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338343/
https://www.ncbi.nlm.nih.gov/pubmed/37344600
http://dx.doi.org/10.1038/s41586-023-06257-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338343/
https://www.ncbi.nlm.nih.gov/pubmed/37344600
http://dx.doi.org/10.1038/s41586-023-06257-4

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