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Regulation of ABC transporters by sex steroids may explain differences in drug resistance between sexes

Drug efficacy is dependent on the pharmacokinetics and pharmacodynamics of therapeutic agents. Tight junctions, detoxification enzymes, and drug transporters, due to their localization on epithelial barriers, modulate the absorption, distribution, and the elimination of a drug. The epithelial barrie...

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Detalles Bibliográficos
Autores principales: Mineiro, Rafael, Santos, Cecília, Gonçalves, Isabel, Lemos, Manuel, Cavaco, José Eduardo B., Quintela, Telma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338412/
https://www.ncbi.nlm.nih.gov/pubmed/36995571
http://dx.doi.org/10.1007/s13105-023-00957-1