Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients

Antibiotic resistance poses a global health threat, but the within-host drivers of resistance remain poorly understood. Pathogen populations are often assumed to be clonal within hosts, and resistance is thought to emerge due to selection for de novo variants. Here we show that mixed strain populati...

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Detalles Bibliográficos
Autores principales: Diaz Caballero, Julio, Wheatley, Rachel M., Kapel, Natalia, López-Causapé, Carla, Van der Schalk, Thomas, Quinn, Angus, Shaw, Liam P., Ogunlana, Lois, Recanatini, Claudia, Xavier, Basil Britto, Timbermont, Leen, Kluytmans, Jan, Ruzin, Alexey, Esser, Mark, Malhotra-Kumar, Surbhi, Oliver, Antonio, MacLean, R. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338428/
https://www.ncbi.nlm.nih.gov/pubmed/37438338
http://dx.doi.org/10.1038/s41467-023-39416-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338428/
https://www.ncbi.nlm.nih.gov/pubmed/37438338
http://dx.doi.org/10.1038/s41467-023-39416-2

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