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A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays
Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used for the evaluation of anti-malarial compounds. Here, to screen for anti-malarial drugs effective against multiple stages of the parasite, we generate a P. falciparum reporter parasite that constitutively expresses...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338434/ https://www.ncbi.nlm.nih.gov/pubmed/37438491 http://dx.doi.org/10.1038/s42003-023-05078-5 |