A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays

Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used for the evaluation of anti-malarial compounds. Here, to screen for anti-malarial drugs effective against multiple stages of the parasite, we generate a P. falciparum reporter parasite that constitutively expresses...

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Detalles Bibliográficos
Autores principales: Miyazaki, Yukiko, Vos, Martijn W., Geurten, Fiona J. A., Bigeard, Pierre, Kroeze, Hans, Yoshioka, Shohei, Arisawa, Mitsuhiro, Inaoka, Daniel Ken, Soulard, Valerie, Dechering, Koen J., Franke-Fayard, Blandine, Miyazaki, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338434/
https://www.ncbi.nlm.nih.gov/pubmed/37438491
http://dx.doi.org/10.1038/s42003-023-05078-5

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