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Utility of C3d and C4d immunohistochemical staining in formalin-fixed skin or mucosal biopsy specimens in diagnosis of bullous pemphigoid and mucous membrane pemphigoid

Bullous pemphigoid (BP) and mucous membrane pemphigoid (MMP) sometimes have overlapping clinical, histopathological, and direct immunofluorescence (DIF) features in the early stages. Complement deposition is an intrinsic component of the patho-mechanism of BP in contrast to MMP. Hence immunohistoche...

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Detalles Bibliográficos
Autores principales: Thakur, Neha, Chatterjee, Debajyoti, Dev, Anubha, Shilpa, Mahajan, Rahul, Handa, Sanjeev, De, Dipankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338454/
https://www.ncbi.nlm.nih.gov/pubmed/37438374
http://dx.doi.org/10.1038/s41598-023-38193-8